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What is Opana?

Opana (oxymorphone) is an opioid pain medication. An opioid is sometimes called a narcotic.

Opana is used to treat moderate to severe pain.

The extended-release form of this medicine is for around-the-clock treatment of severe pain. Opana ER is not for use on an as-needed basis for pain.

Opana may also be used for purposes not listed in this medication guide.

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Before taking this medicine


You should not take Opana if you are allergic to oxymorphone, or if you have:

• severe asthma or breathing problems

• a blockage in your stomach or intestines

• moderate to severe liver disease.

Some medicines can interact with oxymorphone and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.

To make sure Opana is safe for you, tell your doctor if you have ever had:

• any type of breathing problem or lung disease

• head injury, brain tumor, or seizures

• drug or alcohol addiction, or mental illness

• urination problems

• liver or kidney problems

• problems with your gallbladder, pancreas, or thyroid

• if you use a sedative like Valium (diazepam, alprazolam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Versed, Xanax, and others).

Opana may be habit forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it. Selling or giving away Opana to any other person is against the law.

Tell your doctor if you are pregnant or plan to become pregnant. If you use oxymorphone while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

It is not known whether oxymorphone passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

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