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What is methadone?

Methadone is an opioid medication. An opioid is sometimes called a narcotic.

Methadone reduces withdrawal symptoms in people addicted to heroin or other narcotic drugs without causing the "high" associated with the drug addiction.

Methadone is used as a pain reliever and as part of drug addiction detoxification and maintenance programs. It is available only from a certified pharmacy.

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Before taking this medicine

You should not use methadone if you are allergic to it, or if you have:

• severe asthma or breathing problems

• a blockage in your stomach or intestines

Methadone may cause a life-threatening heart rhythm disorder. Your heart function may need to be checked during treatment.

Some medicines can interact with methadone and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take stimulant medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

• heart disease, a heart rhythm disorder, or a personal or family history of long QT syndrome

• any type of breathing problem or lung disease

• a head injury, brain tumor, or seizures

• drug or alcohol addiction, or mental illness

• liver or kidney disease

• urination problems

• problems with your gallbladder, pancreas, or thyroid

• if you use a sedative like Valium (diazepam, alprazolam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Versed, Xanax, and others).

If you use methadone while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant.

Do not breast-feed while taking methadone. This medicine can pass into breast milk and cause drowsiness, breathing problems, or death in a nursing baby.

How should I use methadone?

Methadone may be habit-forming, even at regular doses. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE OF NARCOTIC MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription. Selling or giving away methadone is against the law.

Follow all directions on your prescription label. Methadone can slow or stop your breathing, especially when you start using this medicine or whenever your dose is changed. Never use this medicine in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

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